Hogan C, Serpente N, Cogram P, Hosking CR, Bialucha CU, Feller SM, Braga VM, Birchmeier W, Fujita Y (2004) Rap1 regulates the formation of E-cadherin-based cell-cell contacts
l , Counterflow transport of [ 3 H]GSSG into SLC33A1 reconstituted liposomes for 40 min in the presence of 0.1 to 10 mM unlabelled GSSG
PMID: 19857031
The peptide binds GHRH receptors on anterior pituitary somatotroph cells, activates adenylyl cyclase to increase intracellular cAMP, enhances transcription of the GH gene, and stimulates exocytosis of stored GH from secretory granules
The depletion of glutathione leads to the (i) release of inflammatory cytokines, (ii) the formation of free radicals, and (iii) the inhibition of some cell functions, all of which have been known to cause many chronic degenerative diseases and functional loss with ageing