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Importantly, the observed LBM reduction has not consistently translated into functional impairment, and emerging evidence suggests that GLP-1 RAs may counterbalance this effect by improving muscle quality and metabolism [21]

Side effects of prednisone Common side effects, especially at high doses (40 mg/day or more) or long-term use, include: Insomnia Mood changes Muscle weakness Fluid retention Increased appetite and weight gain Nausea and stomach pain Bloating Headache and dizziness High blood sugar and high blood pressure Serious side effects requiring immediate attention include: Increased risk of infections (avoid exposure to measles or chickenpox) Eye problems (glaucoma, cataracts

What I Actually Do When I'm Not Sure I have a simple personal rule that I've settled on after years of living with type 1 diabetes and using insulin: If I'm genuinely unsure, I replace it

A., Schoeneich, C., Stewart, J

doi:10.1111/jpi.12172