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& Nauck, M

GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes

Overweight and obesity are defined by the World Health Organization as having a body mass index (BMI) 25 253 million global disability-adjusted life years, 6.5 million deaths and almost 62 million years lived with disability from CKD, resulting in a higher global BMI-related burden for CKD than for other conditions traditionally linked to obesity, such as colorectal cancer [4]

The economic burden of obesity-related healthcare costs is staggering, emphasizing the urgent need for effective interventions

Most evidence comes from standard therapeutic doses used for diabetes or obesity management