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Rybelsus was studied as a stand-alone therapy and in combination with other diabetes treatments, including metformin, sulfonylureas (insulin secretagogues), sodium-glucose co-transporter-2 (SGLT-2) inhibitors, insulins and thiazolidinediones, all in patients with type 2 diabetes

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Affected products Unauthorized health products sold online by Prime Research of Sherbrooke, QC, including injectable peptide drugs Issue Health Canada has seized unauthorized injectable peptides drugs, along with unauthorized bodybuilding drugs, sold online by Prime Research as they may pose serious health risks

Gross margins expanded to 71% in the fourth quarter, up from 67% in the fourth quarter of 2024, and gross margin of 66% for the year compared with 61% a year ago