Supporting liver function: These injections assist keep the liver healthy at its best, which is essential for efficient metabolism and fat digestion by reducing the accumulation of fat in the liver
Supplementary material The Supplementary material for this article can be found online at: 17,18-EpETE 17,18-epoxyeicosatetraenoic acid 19,20-EpDPE 19,20-epoxydocosapentaenoic acid ANOVA analysis of variance AUC area under the curve BP biological processes BMI body mass index BCAA branched-chain amino acid BAT brown adipose tissue CDAHFD choline-deficient L-amino acid-defined high-fat diet CC cellular components CON control group DEGs differentially expressed genes DIO diet-induced obese DiHOMEs dihydroxy octadecenoic acids DHA docosahexaenoic acid EPA eicosapentaenoic acid GO gene ontology GLP-1 glucagon-like peptide-1 GLP-1Rs GLP-1 receptors GIP glucose-dependent insulinotropic peptide GIPRs GIP receptors H&E hematoxylin and eosin HDL-C high-density lipoprotein cholesterol HFD high-fat diet HFHFD high-fat, high-fructose diet IRS insulin receptor substrate IL-1 interleukin-1 IPGTT intraperitoneal glucose tolerance test KEGG Kyoto Encyclopedia of Genes and Genomes LA linoleic acid LDL-C low-density lipoprotein cholesterol MTP microsomal triglyceride transfer protein MF molecular functions NOD non-obese diabetic NS normal saline ORO Oil Red O PCA principal component analysis PGE2 prostaglandin E2 PPI proteinprotein interaction RT-qPCR reverse transcription quantitative polymerase chain reaction Sema semaglutide SD standard deviation TZP tirzepatide TC total cholesterol TG triglyceride T1DM type 1 diabetes mellitus T2DM type 2 diabetes mellitus IFN-I type I interferon UCP1 uncoupling protein 1 VLDL very low-density lipoprotein WAT white adipose tissue WHO World Health Organization Glossary References 1
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