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PMID 9845666

Consistently, GLP-1 RA therapy is associated with higher circulating levels of PYY in humans, an appetite-suppressing hormone often co-secreted with GLP-1, and this may be partly mediated by SCFA signaling (58, 63)

They concluded that significant weight regain began eight weeks after stopping AOMs and continued through 20 weeks, particularly for individuals who had previously taken glucagon-like peptide-1 (GLP-1) receptor agonists or those who had experienced greater weight loss during treatment or ongoing lifestyle interventions

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Take it in the dose and duration as advised by your doctor