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The largest section of continuous density in the orthosteric site of conformer 2 is close to receptor residues Y152 1.47 and L141 1.36 , which suggests that these residues act as a hydrophobic anchor for the ligand

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The proportion of cardiac catheterization patients with SGLT2 inhibitor prescriptions before the procedure showed modest but steady growth, increasing from 0.5% in 2018 to 1.6% in 2023 (Figure 4)

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Chaudhuri A, Ghanim H, Makdissi A, Green K, Abuaysheh S, Batra M, et al

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