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These discoveries lay a theoretical groundwork for harnessing its medicinal potential and facilitating its cultivation in low-altitude regions ( Saussurea involucrata cold-resistant characteristics adapt to extreme climates, and the whole herb contains active metabolites with antitumor, anti-inflammatory, analgesic, antioxidant, anti-fatigue, anti-aging, anti-hypoxia, neuroprotective, and immunomodulatory effects, making it an important resource for traditional TM and modern drug development ( S