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The choice depends on individual medical needs and physician judgment 15

A personalized approach to hormone therapy yields the best results

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The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1998)

The series of biochemical transformations begins with the sidechain cleavage catalyzed by the cytochrome P450 enzyme CYP11A1 to give pregnenolone (Figure 7)