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9,10 Likely by virtue of its extensive binding characteristics, in human studies it was determined that linagliptin is cleared mainly by hepatobiliary mechanisms

Harnessing the co-vulnerabilities of amino acid-restricted cancers

10 , e202300419 (2023)

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This observation of increased lifespan and stress resistance may have been afforded by the compensatory increase (2-fold) in expression levels of several genes of the thioredoxin system ( trx-1 , trxr-1 , trxr-2 ) and glutathione S -transferase gene, gst-4 [58]