Ben Lynch is a naturopathic physician and methylation expert
Schaeffer Institute for Public Policy & Government Service
10.1038/s41589-024-01583-8 31 LandryA
Contact your doctor promptly if you experience: Persistent excessive thirst that does not improve with increased water intake, as this may indicate hyperglycemia or other metabolic disturbances Inability to keep fluids down due to severe or persistent vomiting Signs of significant dehydration including dizziness, confusion, rapid heartbeat, or very dark urine Decreased urination or no urination for 8 hours or more Severe or persistent abdominal pain (if pancreatitis is suspected, discontinue Zepbound immediately and seek medical attention) Symptoms suggesting acute kidney injury such as swelling in legs or feet, persistent nausea, or changes in urination patterns Seek immediate medical attention for: Severe dizziness or fainting , particularly if accompanied by chest pain or shortness of breath Signs of severe dehydration including extreme weakness, sunken eyes, or altered mental status Symptoms of diabetic ketoacidosis in patients with diabetes (uncommon in type 2 diabetes on tirzepatide but possible), including excessive thirst with fruity-smelling breath, rapid breathing, or confusion Patients with diabetes should check blood glucose levels when experiencing unusual thirst and follow sick-day management guidelines from the American Diabetes Association, including checking for ketones during illness
Efficacy and Safety of Semaglutide 7.2 mg in Obesity: The STEP UP Trial
