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Abnormalities in various metabolic pathways such as glucose 80 or amino acid metabolic system 81 in chondrocytes have been implicated in activating catabolic cascades in osteoarthritic cartilage 82

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Aruoma OI, Whiteman M, England TG, Halliwell B (1997) Antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite