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Autophagy is crucial for longevity [80], but declines with age and contributes to aging-associated diseases, such as neurodegeneration [81]

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Phase 2 trials testing 9 mg, 10 mg, and 16 mg doses have shown promising results with weight loss potentially approaching 20% or higher at maximum doses

A double-blind, placebo-controlled trial related to the effects of melatonin on oxidative stress and inflammatory parameters of obese women

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