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Mechanistically, this complementarity is plausible: while surgery provides mechanical gastric restriction and alters gut hormone profiles, its inability to fully correct the underlying energy homeostasis dysregulation in MC4R deficiency often leads to long-term weight regain [43,45]
Portion control becomes easier on GLP-1 therapy due to enhanced satiety signals, but patients should still practice mindful eating
Below is a summary of common and rare reactions: Medical Guidelines Individuals with asthma should use caution, as bronchoconstriction may occur [6]
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