In the UK, several GLP-1 receptor agonists are licensed by the Medicines and Healthcare products Regulatory Agency (MHRA), each with specific indications: semaglutide (Ozempic for type 2 diabetes, Wegovy for weight management), dulaglutide (Trulicity for type 2 diabetes), and liraglutide (Victoza for type 2 diabetes, Saxenda for weight management)
doi: 10.1007/s10571-021-01084-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 47.Mason BL, Wang Q, Zigman JM
In the case of canagliflozin, randomized clinical trials have demonstrated that it improves hepatic insulin sensitivity, as well as insulin secretion and clearance in patients with T2DM
For men over 40, this is particularly relevant
GLP-1 prescriptions for weight-loss In a separate analysis between 2020 and 2023, one HealthVerity closed claims dataset had more than 1.5 million patients who had at least one prescription for tirzepatide or semaglutide