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Important Safety Information for Zepbound (tirzepatide) Injection Warning: Risk of Thyroid C-Cell Tumors Studies in rodents have shown that tirzepatide, the active ingredient in Zepbound , can lead to thyroid tumors, including thyroid cancer

Madrigal is requesting approval of resmetirom under the FDAs accelerated approval pathway

It has been observed that fibroblasts might be encouraged to adopt characteristics similar to cardiomyocytes under certain laboratory conditions

Additional studies have shown mixed results and were limited by study design for example, exposure was based on prescription history and lack of data on fetal outcomes like miscarriage or pregnancy loss

PMCID: PMC6305861