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Studies have shown that HLA-DR2 haplotypes, particularly DRB5*01 + -DRB1*1501 + -DQB1*0602-, may play a role in the development of MS [152, 153]

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Since 2006, glucagon-like peptide-1 receptor (GLP-1R) agonists have caused a dramatic change in the treatment of type 2 diabetes, with clinically relevant and sustained effects on glycaemic control and body weight combined with cardioprotective mechanisms [3, 4]