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Marcel Monnier and Lucien Hsli at Basel had reported, in cross-circulation experiments dating back to the 1960s, that low-frequency electrical stimulation of the intralaminar thalamic nuclei in donor rabbits produced a humoral factor that, when transferred to awake recipient rabbits via dialysed cerebral venous blood, induced an EEG pattern resembling slow-wave sleep

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Originally discovered in the 1970s, GHK-Cu plays a significant role in stimulating collagen synthesis and improving tissue repair

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Initial laboratory assessment should include a complete blood count and serum vitamin B 12 level