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M., Pound, C
The approved Canadian indication is the reduction of excess visceral adipose tissue in treatment-experienced HIV-infected adult patients with lipodystrophy, with eligibility criteria including waist circumference thresholds and CT-confirmed visceral adipose tissue measurements
That showed basically binding of either dynorphin or whatever ligand to the kappa opioid receptor, basically sensitizes the Mu opioid receptor to the feel-good endorphins, and also changes
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