Recent examples include degraders of the WIZ transcription factor, such as dWIZ-1 and dWIZ-29, which induce fetal hemoglobin expression through selective WIZ degradation and demonstrate the expanding scope of molecular glue technologies [8]
GSH, in such a high intracellular concentration, contributes to preventing these abnormal effects
In soluble GSTs belonging to the classes alpha, mu, pi, and sigma, the thiolate anion is being stabilized by hydrogen bonding with a tyrosine residue and by interactions with hydrating water molecules 34 whereas in other GSTs a serine is utilized 38
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1a), a time when most of the newly produced HSV-1 capsids exit the nucleus