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Since hyperinsulinemia is a primary driver of excess ovarian androgen production in PCOS, improving insulin sensitivity can lower testosterone through a mechanism that is independent of weight loss alone

doi: 10.1016/j.clim.2020.108544 29 JainS

Given these high numbers, overlap is expected, especially with certain skin diseases such as psoriasis and hidradenitis suppurtiva (HS) due to shared inflammatory pathways and risk factors