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Taken together, these results indicate that OsDHAR has potent chaperone-like properties and is capable of protecting proteins from precipitation and heat-induced loss of enzymatic activity, suggesting that OsDHAR is a potent inhibitor of stress-induced protein aggregation

Metabolic assays Isolated lung activated ILC2s were cultured in RPMI 1640 with 5% FBS, 2 mM L-glutamine, 100 U/ml Pen-Strep in addition to rmIL-2 (10ng/mL) and rmIL-7 (10ng/mL) at 37 C

The DOT1L inhibitor EPZ-5676: Safety and activity in relapsed/refractory patients with MLL-rearranged leukemia

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