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It can increase resting heart rate, and patients with cardiovascular disease need to approach it cautiously

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Am J Respir Crit Care

Adverse Reactions (6.1).] Add-on Combination Therapy with Insulin (with or without Metformin) A total of 641 patients with type 2 diabetes participated in a 24-week, randomized, double-blind, placebo-controlled study designed to assess the efficacy of JANUVIA as add-on to insulin therapy (with or without metformin)

Goldstein, along with Abraham White, co-discovered the thymosins in the 1960s at Albert Einstein College of Medicine