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These include the size of the drug molecule, how tightly the drug binds to proteins in the blood, how easily the drug dissolves in fat, and how long the drug stays in the body

In a rat model of ischemic stroke after middle cerebral artery occlusion (MCAO), IN DFO significantly reduced infarct volume and neurological deficits (Hanson et al., 2009)

The slides cooled at 4 C for 5 min, and then were slowly opened