& Seddon, P
Antalis CJ, Uchida A, Buhman KK, Siddiqui RA
Poppe 1 , Alexander Khaw 2 , Darren Ferguson 3 , David Volders 3 , Grant Stotts 4 , Ariesteidis Katsanos 5 , Gregory Jacquin 1 1 Centre Hospitalier de lUniversit de Montreal, Montreal, Canada, 2 London Health Sciences Centre, Western University, London, Canada, 3 Dalhousie University, Halifax, Canada, 4 Ottawa Hospital Research Institute, Ottawa, Canada, 5 McMaster University, Hamilton, Canada Background and Aims: There are several possible sedation strategies during endovascular therapy for acute ischemic stroke, including general anesthesia, conscious sedation, and local anesthesia
AS: Writing review and editing
Proven alternatives deliver comparable results with established safety: tirzepatide monotherapy produces 15-22% weight loss with FDA approval and extensive clinical data, while CagriSema (cagrilintide + semaglutide) delivers 15-25% weight loss with Phase 3 trial validation and clearer path to medical acceptance
