As mechanistic insights into iron homeostasis, lipid peroxidation, and immunometabolic interactions continue to deepen, alongside progress in drug delivery, gene editing, and regenerative medicine, therapies targeting ferroptosis may represent a promising new paradigm in OA management, ultimately enhancing joint function and overall quality of life for affected individuals
The liver, being a thermosensitive organ, acts both as a target of injury and an "amplifier" of inflammation
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These patients experienced an average weight loss of about 18 pounds, with a reduction in fasting plasma glucose (FPG) of 89.7 mg/dL, and a reduction in the mean daily glucose (MDG) of 105.9 mg/dL
This hormone signals fullness, slows gastric emptying, and helps regulate blood sugar levels