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Tangent An observational study published in November 2024 found semaglutide resulted in a substantially decreased risk of alcohol-related hospitalizations, suggesting the drug may be effective in treating alcohol use disorder

4.2 Lack of specific biomarkers and translational limitations of therapeutics The clinical translation of ferroptosis-targeted strategies is bottlenecked by two critical barriers: the absence of specific, standardized biomarkers for ferroptosis in renal tissues and biofluids, and the suboptimal pharmacokinetic and safety profiles of current ferroptosis modulators