Coverage that did exist was commonly restricted by prior authorisation requirements, step therapy mandates (requiring failure on cheaper drugs first), and BMI thresholds stricter than the approved labelling
While AstraZeneca at the time did not disclose specific data, the FDA in its news release on Wednesday said treatement with Imfinzi reduced the risk of death by 27% versus placebo, while also improving PFS by 24%
Nautiyal: Genetics is important, but I would say the vast majority are lifestyle-related
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