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Dementia 23(3):493511 Thomson WM, Barak Y (2020) Tooth loss and dementia: a critical examination

The combination of GPX4 inhibitors with immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis increases the proportion of CD8 + T cells, enhances their cytotoxic activity and induces ferroptosis, thereby promoting chemotherapy resistance [42]

Three disulfide bonds (Cys336Cys361, Cys379Cys432, and Cys391Cys525) stabilize the sheet structure of the core, while a fourth pair (Cys480Cys488) connects loops in the distal end of the RBM [43]