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[published online ahead of print, Aug 11]

Martin Holst Lange, Novos head of development, estimated that 40% of people who live with type 2 diabetes also live with CKD

Many users report shifts in mood and psychology that feel dramatic - sometimes positive, sometimes unsettling

Common early side effects include nausea, mild bloating, and loose stools, which typically resolve within 4 to 8 weeks

Hypoglycaemia Risk Whilst GLP-1 agonists alone carry a low intrinsic risk of hypoglycaemia due to their glucose-dependent mechanism, the risk increases substantially when combined with insulin or sulphonylureasmedications commonly prescribed to older adults with longstanding diabetes