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This further illustrates that reducing the number of hydrogen bond donors/acceptors usually can improve the oral bioavailability of small molecules

AstraZeneca and Amgens Tezspire (tezepelumab) has been approved in the US as an add-on maintenance treatment for adults and adolescents (12+) with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP) marking a major advancement for patients living with this epithelial-driven inflammatory condition

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Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes