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NHS access requires meeting NICE criteria: BMI 35 kg/m (or 32.5 kg/m for certain ethnic groups) with weight-related comorbidities, referral to specialist weight management services, and demonstrated response to treatment at defined review points

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Readers researching the broader hepatocyte growth factor / c-Met pathway for cognitive indications should be aware that Fosgonimeton (development code ATH-1017), a structurally distinct small-molecule prodrug developed by Athira Pharma as an HGF positive modulator, has been investigated in three clinical trials in dementia indications

Furthermore, the gut microbiome is highly complex, with its composition varying widely between individuals

PENA CHAVARRIA, A., SWARTZWELDER, J.C., VILLAREJOS, V.M., KOTCHER, E., & ARGUEDAS, J