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The aim is to prevent inadvertent exposure during the first trimester

10.1016/j.bbrc.2018.02.061 95 LiuJ.KuangF.KroemerG.KlionskyD

In MCAO rat brain and in OGD/R-treated SK-N-SH cells in vitro , caffeic acid decreased the expression of TFR1 and ACSL4, and increased the synthesis of glutathione via the Nrf2 signaling pathway to inhibit ferroptosis ( vivo and in vitro models, evidenced by excessive accumulation of iron ions and inactivation of the ferroptosis defense system