The Cardiovascular Safety Picture Its worth stepping back to look at the broader cardiovascular evidence for GLP-1 medications, because the mild heart rate increase exists within a much more positive overall cardiac profile
In a phase 2b trial, cotadutide reduced glycemia and body weight and improved metabolic-dysfunction associated steatotic liver disease (MASLD) 18
Able to stimulate insulin production in the body, the hormone helps to regulate blood sugar levels and suppress appetite
These can include hormonal shifts, stomach troubles, and even changes in menstrual cycles
Clinical symptoms common to patients with UC include fever, tiredness, weight loss, and bloody diarrhea, which is another common symptom (Boal Carvalho and Cotter 2017)