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About 95% of BAs in the intestinal lumen are subsequently reabsorbed primarily in the terminal ileum by the apical sodium-dependent bile acid transporter (ASBT)

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Esto representa una barrera para muchas personas y ha generado la necesidad de explorar alternativas no inyectables que mantengan la eficacia sin sacrificar la comodidad del paciente

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Weight loss is a secondary benefit for which these drugs were originally designed

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Without it, a significant portion of your weight loss comes from lean mass rather than fat, which slows your metabolism and makes future weight regain even more likely

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