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They play a key role in: Allergic reactions Wound healing Immune defense against pathogens Regulating inflammation When activated, mast cells release granules filled with bioactive substances, including: Histamine Tryptase Prostaglandins Leukotrienes Cytokines This process is called degranulation and in normal situations (e.g., in response to an insect sting or parasite), it's protective

Like tirzepatide, it acts on GLP-1 and GIP receptors, but it also activates glucagon receptors

A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist

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One example from each of the common diabetes classes is listen in Table 4 since other medications in the same class typically have similar costs