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During the first week, dramatic physical changes are uncommon

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Redox Biology

Clinical studies in normal subjects showed GH secretion of 1434.8 plus or minus 393.0 after GHRP-6 administration alone, compared to 483.7 plus or minus 99.2 after GHRH alone

Seemingly in opposition to the theory that the diminished GH secretion of older age is a net detriment are observations that animal models of congenital GH deficiency have remarkably increased lifespan, and that humans with congenital GH deficiency may have decreased rates of age-related diseases such as diabetes and cancer