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In recent years, advances in cryo-electron microscopy (cryo-EM) have enabled structural determination of a large number of class B1 GPCRs bound to their endogenous agonists, and coupled to G s , including that of the GLP-1R, which confirm engagement of these peptides with both the ECD and the TMD 10,11,12,13,14,15,16,17,18,19,20,21
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Statements Author contributions YY: Visualization, Methodology, Validation, Formal analysis, Conceptualization, Project administration, Software, Investigation, Writing review & editing, Resources, Data curation, Writing original draft
Oxytocin signalling in dendritic cells regulates immune tolerance in the intestine and alleviates DSS-induced colitis
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