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This approach requires baseline electrocardiogram (ECG), blood pressure monitoring every 2 weeks, and willingness to discontinue phentermine immediately if adverse cardiac signs appear

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MCC950, a selective NLRP3 inflammasome inhibitor, successfully suppressed TGF-1 + IL-1-induced NLRP3 inflammasome activation, as indicated by the downregulation of caspase-1 p20 (Fig