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Klein et al

Neuroendocrine and neuroimmune research together allow us to conclude that stress, understood as distress or toxic stress, through the systemic effects of cortisol and norepinephrine, is capable of altering brain activity, by means of various mechanisms, still to be fully discovered in their complexity, that seem to center on two fundamental pathways: alteration of the structure of brain areas and circuits, induction of neuroinflammation and oxidative stress

These powerful antioxidants help fight free radicals in body which helps prevent oxidative stress and premature aging of skin

2 In those with a genetic predisposition, psoriasis develops through a pathway of interactions following an environmental inflammatory trigger toward a keratinocyte, such as stress, trauma, or micro-organism action

DOI: 10.4103/1735-5362.283820