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Both are classified as research chemicals and are prohibited under the World Anti-Doping Agency (WADA) Prohibited List in the S2 category covering peptide hormones, growth factors, related substances, and mimetics a classification that applies year-round to athletes subject to WADA-compliant testing

Severe appetite suppression below 1,200 calories daily can cause fatigue, nutrient deficiencies, and metabolic slowdown

Greasy, fried, and very rich foods are the most common dietary triggers for nausea on GLP-1 medications

In Phase 2 trials, retatrutide was started at 12 mg subcutaneously once weekly and gradually titrated to maintenance doses of 4 mg, 8 mg, or 12 mg once weekly

How Deficiency Affects Detoxification