This means it doesnt compete with the liver enzymes that metabolise many other medications, reducing the likelihood of drug interactions
Still, the study determined that the overall incidence of the condition was exceptionally low, with just 1.4 additional cases per 10,000 patient-years of observation calculated as the number of patients multiplied by the years they were monitored among those taking Ozempic compared to users of other diabetes medications
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Headaches accompanied by visual disturbances, confusion, or neck stiffness warrant same-day medical review to exclude serious neurological conditions
NICE first recommended the drug in draft guidance 2022, after a clinical trial of just under 2000 volunteers found that people lost on average 12% more weight with semaglutide alongside supervised weight loss coaching (BMJ 2023;380:556)
