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Researchers dont know precisely why semaglutide and constipation can often go hand-in-hand, but they theorize its related to how the medication works on your digestive system: It slows your digestion: Semaglutide is a glucagon-like peptide-1 receptor ( GLP-1 ) agonist that delays gastric emptying the movement of food from your stomach into your intestines

Bigger blood sugar swings More reactive hypoglycemia Sugar + carb cravings Feeling hungry again shortly after meals Ghrelin (your hunger hormone) becomes more unpredictable Some women suddenly experience: Constant hunger Stronger appetite in the luteal phase Emotional eating tendencies Difficulty feeling satisfied Cortisol becomes more reactive Perimenopause is a time of reduced stress resilience, and cortisol + blood sugar are dance partners

Fat supports hormone function, helps your body absorb nutrients, and can help you feel satisfied longer

Heres how to do this: Wash your hands: Wash your hands with soap and warm water, and thoroughly scrub between fingers, on the backs of hands, and under fingernails

Slower digestion often means stool moves more slowly, leading to bloating, discomfort and fewer bowel movements