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The 61-year-old company is initiating a business and brand transformation, rethinking its positioning in a weight loss market upended by the rise of GLP-1 anti-obesity drugs including Ozempic

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What safety concerns has the FDA raised about this category

Administration of semaglutide at the dose regimen of ~ 90 g/kg/day failed to evidence significant weight loss but more importantly, led to alteration of cortical bone microarchitecture, represented by lower cortical thickness, and ultimately to a significant decrease in bone strength [69]

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