glp-1 cold Chronic stress promotes inflammation and ER stress via inhibiting GLP- 1R signaling, and exacerbates the risk of ferroptosis in the liver and pancreas From Lab to Last Mile:

According to the SmPC, nausea is very common (affecting approximately 44% of patients), while vomiting, diarrhoea, constipation, and abdominal pain are common side effects

The exception: if you take insulin or sulfonylureas alongside your GLP-1 medication

However, the post-menopausal drop in estradiol levels exacerbates this mitochondrial dysfunction

While mild cold sensitivity is a common and generally benign experience during treatment with incretin-based medications, certain symptoms warrant medical evaluation to rule out underlying conditions or complications

Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD