glutathione tablets for fair skin MOUNTAINOR Liposomal Glowing, Whitening & Brightening Clear with Vit C Glutathione 5000 Mcg Capsules Anti-Oxidation

Kalman D.S., Feldman S., Samson A., Krieger D.R

Depression score was significantly higher in the group with low serum levels of vitamin C, showing the importance of plasma level of vitamin C in depression attenuation (Marazzi et al

Bioregulator theory and mechanism Khavinson's bioregulator concept: Each organ produces specific regulatory peptides These peptides maintain tissue homeostasis With aging, peptide production declines Supplementing organ-specific peptides restores function Gene regulation is key mechanism How Cartalax works (theory): Enters cartilage cells (chondrocytes) Binds to specific DNA sequences Upregulates cartilage-protective genes Downregulates degradative genes Optimizes cartilage matrix production Gene expression changes: Upregulated (increased): Collagen Type II: Main cartilage structural protein Proteoglycans: Water-holding molecules Aggrecan: Cartilage compressive strength TGF-: Growth factors for cartilage Chondrocyte proliferation genes Downregulated (decreased): Matrix Metalloproteinases (MMPs): Cartilage-degrading enzymes Inflammatory cytokines: IL-1, TNF- Apoptosis genes: Prevents cartilage cell death Oxidative stress markers Mechanism comparison: Why bioregulation different: Works at DNA/gene level (root cause) Tissue-specific (only cartilage affected) Long-lasting effects (genes stay regulated) Cyclic dosing sufficient (vs continuous) Preventive and restorative Compare to other mechanisms and joint peptides

In order to exploit the pro-cognitve properties of AnglV like molecules more metabolically stable analogs needed to be developed

Future Research Directions for SLU-PP-332 and 5-Amino-1MQ The research community will continue to find new applications and research areas for both compounds