Natalie Mayslich, Chief Operating Officer of ISSA, captures the urgency clearly, The weight loss landscape is changing dramatically, and trainers and coaches need more than sciencethey need strategies to best help their clients succeed. Beyond the Prescription: Coaching for Sustainable Change GLP-1s are a catalystnot a cure
Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial
The measures included: Appendicular and trunk fat-free mass (proxy for lean muscle) Whole-body and trunk fat mass Body-fat percentage Waist-to-hip ratio Key Findings The researchers found that for every 1-unit reduction in BMI linked to GLP-1 mimicry: Fat mass decreased by ~7.9 kg Lean mass (muscle) decreased by ~6.4 kg Body-fat percentage dropped by ~4.5% In other words, fat loss exceeded muscle loss in both absolute and relative terms, which supports the use of GLP-1 drugs as a viable treatment for obesity
By contrast, medical weight loss addresses the root causes of weight retentionmetabolic dysfunction, insulin sensitivity, and appetite dysregulation
I think this stuff works, but with a healthy diet and exercise