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Even too much exercise (overtraining) generates added free radicals High amounts of emotional or physical stress

By lowering the overall oxidative load, glutathione may allow azelaic acid to work more efficiently on the baseline pigmentation, rather than constantly fighting a new influx of pigment triggered by daily environmental damage

References are provided for research orientation only and describe preclinical or experimental work

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses