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Altern Ther Health Med 21(Suppl 3):2832 Behera J, Bala J, Nuru M, Tyagi SC, Tyagi N (2017) Homocysteine as a Pathological Biomarker for Bone Disease

SsTyrA and OiTyrA were chosen as they are located at key phylogenetic boundaries within clade I and contain residues required for cofactor binding and catalysis (Figure S2, Data S2)

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This epigenetic modification suppresses SLC7A11 transcription, thereby reducing xCT expression, impairing cystine uptake, and limiting intracellular GSH synthesis, ultimately heightening neuronal vulnerability to ferroptosis (92)