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Th17 cells The cytokines IL-1, TGF-, IL-6, and IL-23, as well as the transcription factor RORt, regulate the development of Th17 cells

Le glutathion rduit (GSH) intervient plusieurs niveaux de cette cascade biochimique

(223) demonstrated that iNOS-derived NO causes a transient increase in free zinc concentration in the nucleus that correlates with the translocation of MTs to the nucleus, where they rapidly exchange zinc with zinc-finger transcription factors and regulate gene expression

De Koninck, Y

Conclusions This paper demonstrated that aluminum oxalate caused symptoms similar to oxaliplatin-induced peripheral neuropathy, and showed for the first time that aluminum chelation using GSH could be the solution